Cholibrium is formulated using a blend of 10 mushrooms that work in different ways to support heart health. Some of the mushroom extracts are adaptogens, for example, which means they help your body respond to physical and cognitive stressors. Adaptogens are ideal for stress management and stress response, and some studies show mushroom extracts can control cortisol (stress hormone) levels, which could help with heart health. Other ingredients in Cholibrium are antioxidants, which means they help support healthy inflammation throughout your body. High levels of inflammation are associated with an increased risk of disease and illness. Plus, heart inflammation can lead to high blood pressure and poor cardiovascular health. Cholibrium floods your body with a blend of antioxidants to support blood pressure and inflammation in various ways. Many of the mushroom extracts in Cholibrium are backed by centuries of use in traditional medicine. Some have been used in traditional Japanese, Chinese, and Siberian medicines for centuries, for example, to support health and wellness. One mushroom extract in Cholibrium, native to Brazil, continues to be a popular natural medicine throughout the country. By combining multiple mushroom extracts from around the world together, Simple Promise aims to have created the ultimate health supporting, immune boosting supplement.